生物离子制剂/LDN193189,2.03mg/1/SM-005
商品编号:
SM-005
品牌:
biopioneerinc
市场价:
¥2600.00
美元价:
1300.00
产品分类:
细胞转染
公司分类:
Cell_transfection
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
LDN193189 is a highly potent cell permeable small molecule BMP inhibitor; inhibiting BMP type I receptors ALK2 (IC50: 5 nM), ALK3 (IC50: 30 nM) and ALK6 (TGFβ1/BMP signaling) and subsequent SMAD1, SMAD5, and SMAD8 phosphorylation (1, 2). It only has weak effect on ALK4, ALK5 and ALK7. LDN-193189 shows significant in vivo clinical utility, inhibiting FOP and ectopic ossification and a potential agent in the treatment of NSCLC lung tumors. Using LDN193189 can accelerates developmental timing and converts human pluripotent stem cells into nociceptors (3).
品牌介绍
BP-Fectin TM哺乳动物细胞转染试剂是阳离子聚合物的专有配方,为实现高转染效率,低细胞毒性和易用性而优化。BP-Fectin TM转染试剂可替代许多其他转染技术,包括磷酸钙共沉淀,电穿孔,显微注射,生物弹颗粒递送以及与DEAE-葡聚糖的复合物形成。BP-凝集素转染试剂在哺乳动物和昆虫细胞的稳定和瞬时转染中均具有出色的性能。1.5毫升毫升的BP-Fectin TM转染试剂可提供足够的试剂来进行多达400x1ug的转染。BP-Fectin TM 转染试剂以即用型无菌溶液形式提供,是多孔板形式的高通量转染的理想选择。