生物离子制剂/SB431542，5.76mg/1/SM-011
商品编号：
SM-011
品牌：
biopioneerinc
市场价：
¥2700.00
美元价：
1350.00
产品分类：
细胞计数仪
公司分类：
Cell_counter
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
SB 431542 is an inhibitor of the transforming growth factor-beta 1 (TGF-β1) activin receptor-like kinases (ALKs). It is a selective and potent inhibitor of ALK-4, -5 (IC50 = 94 nM) and -7. SB431542 inhibits endogenous activin and TGF-β signaling without affecting more divergent BMP signaling utilizing ALK-1, -2, -3, and -6 (1,2). It has no effect on the other, more divergent ALK family members that recognize bone morphogenetic proteins (BMPs) such as ALK2, ALK3 or ALK6. It has also no effect on components of the ERK, JNK, or p38 MAP kinase pathways or on components of the signaling. SB 431542 at 1μM stimulates proliferation, differentiation, and sheet formation of endothelial cells derived from embryonic stem cells (3).
Biopioneer Brand:
品牌介绍
BP-Fectin TM哺乳动物细胞转染试剂是阳离子聚合物的专有配方，为实现高转染效率，低细胞毒性和易用性而优化。BP-Fectin TM转染试剂可替代许多其他转染技术，包括磷酸钙共沉淀，电穿孔，显微注射，生物弹颗粒递送以及与DEAE-葡聚糖的复合物形成。BP-凝集素转染试剂在哺乳动物和昆虫细胞的稳定和瞬时转染中均具有出色的性能。1.5毫升毫升的BP-Fectin TM转染试剂可提供足够的试剂来进行多达400x1ug的转染。BP-Fectin TM 转染试剂以即用型无菌溶液形式提供，是多孔板形式的高通量转染的理想选择。
